The Pervasiveness Of Undertreated Hypothyroidism

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tex
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The Pervasiveness Of Undertreated Hypothyroidism

Post by tex »

Hi All,

I've listed some preliminary information first, that I consider to be important, (especially to anyone unfamiliar with my thyroid history), but if you get bored, you can always cut to the chase, below.

Soon after my first abdominal surgery, (5 years and 9 months ago), I began to notice that somewhat surprisingly, (since I considered myself to be in generally good physical condition), I was often short of breath, gained weight very easily, (weight was never a problem, prior to that, except for the times that I got down to hide and bones, during severe diarrhea episodes), and the outer third of my eyebrows were disappearing. :shock: I still wonder if the anesthesia or something else connected with the surgery had something to do with that, but anyway, since those are symptoms of hypothyroidism, I asked my doctor to check my TSH, free T3, and free T4. He forgot to check the free T3, but the TSH, (and one or two other things that he checked), were within the normal range. My free T4, however, was slightly below range.

Naturally, he insisted that as long as the TSH level was at mid-range, (which it was, since the lab he uses was using the out-of-date, extended normal range), I was fine, and no thyroid supplement was needed. I pointed out the below-range T4 result, so he agreed to write a script for a minimum dose of synthroid, to allow me to see if it might help. My next test results showed the TSH down slightly, (but still mid-range), and the free T4 was barely in the normal range, (at the very bottom). To him, that looked great, since my results were all "in the normal range". At my request, though, he agreed to try doubling the dose, so we did. My labs looked slightly better, but my symptoms did not change significantly, so he agreed to write a prescription for an equivalent dose of Armour.

That seemed to help a little, but my eyebrows continued to slowly atrophy, my weight stabilized at a higher level than previously, and I wasn't quite as prone to being out of breath, as I had been, prior to the treatment, so we settled there, and I didn't ask to try a higher dose, since I didn't want to risk tachycardia, or any of the bad stuff that goes with overdosing on thyroid hormone supplement. :lol:

Well, the years rolled by, and my last thyroid test, (14 months ago), showed my T3-Uptake to be in the lower third of the normal range, my free T4 was barely above the low side of the normal range, and my total T4 was below normal. My TSH, though, was below mid-range, (at 1.105, for a "normal" range of 0.34 to 5.6), so that number looked great, so like an idiot, I didn't even bring up the low T4 numbers at the followup, since really, the results weren't much different than what they had typically been. :roll:

Since my second TIA, (at least, that's what they decided to call it), 15 months ago, I've been declared a high stroke risk, so I've been taking stroke risk-reducing drugs such as Plavix, (an expensive blood thinner), lisinopril, (an ACE inhibitor, to lower BP), and metoprolol tartrate, (a beta blocker, to lower heart rate). Prior to taking those drugs, my labs were all pretty much normal for my age, (including my heart rate). As soon as I started taking the drugs, of course, they lowered my BP, and my heart rate, so that now, my BP and my heart rate are below normal, for my age. This morning, for example, my BP was 111/64, and my heart rate was 57. The problem with this, is that 57 is in the bradycardia range, (too low), especially for someone my age - I ain't no spring chicken, any more, :lol: and I'm not a professional athlete, so my resting heart rate should be significantly higher. Anything below 60 is considered bradycardia, and anything below 50 is known to carry a risk of cardiac arrest. :shock:

Of course, my heart rate isn't always this low - most of the time it's above 60. Prior to about 6 or 7 weeks ago, it was always above 60. Lately, though, it's occasionally showing up below 60. And, if my eyebrows were a species, they would probably be getting close to qualifying for listing on the endangered species list. :lol: Soooooooo, I'm beginning to suspect undertreatment of hypothyroidism. (Bradycardia is also a symptom of hypothyroidism).

I guess the point that I'm trying to make is that all this time, I've suspected that I was being undertreated for hypothyroidism, but it didn't seem to be a big deal, since, (like MC), that's not usually a fatal condition. Now that I'm taking drugs to artificially suppress my BP and heart rate, though, and I'm seeing a few numbers that don't look good, I'm beginning to wonder how these enter into the equation. Obviously, the drugs complicate the situation, making it more difficult to draw firm conclusions about symptoms.

I have also noticed that my shortness of breath, (dyspnea), is becoming more of a problem. A few months ago, I started to take a magnesium supplement, and that seemed to alleviate the problem, for a while, but now the symptoms are on the increase, again, even though I'm still taking the magnesium. Since shortness of breath can be a symptom of congestive heart failure, I don't consider it something to just ignore.

I've made what I consider to be a breakthrough observation, though, (at least I think it's a breakthrough observation): even when I'm having the most noticeable dyspnea symptoms, (late at night, when I'm trying to fall asleep, and the dyspnea is keeping me awake), my oxygenation level is still typically in the 98% range, and my heart rate is typically in the bradycardia range, (around 56 to 57, usually). I'm not a medical professional, but that suggests to me that my heart is working fine, but something is causing it to beat too slowly, and that something is probably inadequate thyroid hormone, since it would be logical that thyroid hormone would be becoming depleted by then, (since I take the Armour first thing in the morning).

I take the lisinopril, (10 mg), and metoprolol tartrate, (25 mg), at bedtime, and I take a second tablet of the metoprolol tartrate after breakfast. I think that the metoprolol gets used up pretty quickly, so that's certainly part of the reason for my low heart rate during the night, but that shouldn't cause shortness of breath, and I have a hunch that the heart rate wouldn't be so low if plenty T3 were available.

I guess what I'm trying to say is that I have a hunch that undertreated hypothyroidism is causing symptoms that mimic congestive heart failure. Thinking back, when I originally mentioned the shortness of breath problem to my doctor, the first thing he did was to check my oxygenation level, and pronounce me fine, because it was 98%, so I suppose that's why he's never been concerned about it. Anyone have any thoughts on this?

Love,
Tex
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GALAHAD!!!!!!!!!!

Post by barbaranoela »

I am not an Xpert with medical issues but I certainly dont like what I have read!!!!!! Sounds like a second opinion is much needed---and U R smart enuf about your body--

As U know I was taken off my meds for hyPER thyroidism--bout a year or so ago----I got panicky but after hearing my thyroid doc. Xplain everything she settled me down---I just went yesterday for a sonar gram---blood work and all that jazz----and all is A-OK--2 much meds for the HYPER could also cause issues---

I wish U could come here and see my doctors--of course I dont mean to sound as tho U arent being taken care of properly but now U have me and I am sure everyone else very concerned---


Follow your hunch--cus your *hunches* usually are correct~~~~~

luve ya--
Barbara also mrs. columbo is concerned~~~



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Post by tex »

Barbara,

I'm sorry - I didn't mean to suggest that there's anything to be concerned about. It certainly hasn't concerned my doctor, for over 5 years, now. At my last office visit, (last month), he was as happy as a lark, and impressed that I'm doing so well.

I was just posting about how thyroid issues can appear to be something else. If I thought for a minute that something serious was going on, I'd be on the phone, setting up an appointment to have some tests done.

I think my next appointment is in October or November. I plan to go over all this with him, then.

Luve,
Galahad
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Post by starfire »

A quote from "Overcoming Thyroid Disorders" by Dr. David Brownstein:
"Every single muscle, organ and cell in the body depends on adequate thyroid hormone levels for achieving and maintaining optimal functioning."

If that's true (I assume it is) then every single thing that can go wrong with us can be affected by our thyroid hormone levels. That's actually kind of scary.

Have you considered taking iodine to give your thyroid a little boost?

Love, Shirley
When the eagles are silent, the parrots begin to jabber"
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Post by tex »

Shirley wrote:That's actually kind of scary.
Yes it is, but the really scary part is how casually most doctors seem to handle thyroid issues - as long as the TSH is in what someone has arbitrarily declared to be a "normal" range, they're happy, without regard to whether or not their treatment actually resolves the patient's symptoms. :roll:

No, I've never considered taking iodine. I thought that was only a treatment for someone with goiter - I've never had that symptom.

Guess I'd better research that a bit.

Thanks.

Love,
Tex
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Post by MBombardier »

Interesting. That seems to be my word of the day, lol. I did not know that bradycardia was a symptom of hypothyroidism. As you may remember, I tapered off atenolol about two months ago. I was concerned that I would have tachycardia, since the atenolol was keeping my heart rate down, but I only had a few episodes early on and none in quite some time. In fact, when I take my BP in the mornings, my BP is the same as it was with the atenolol and so is my heart rate--the upper 50's or low 60's.

The visit to the endocrinologist my GP referred me to was pointless, except I strong-armed him into upping my dose of Armour to 60mg. I feel pretty good, but he only gave me three refills, so I imagine i will be fighting this battle again pretty soon.
Marliss Bombardier

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Post by starfire »

Another quote from Dr. Brownstein (Iodine, why you need it, why you can't live without it):
"Every cell in the body contains and utilizes iodine. Iodine is concentrated in the glandular system of the body. The thyroid gland contains a higher concentration of iodine than any other organ of the body. Large amounts of iodine are also stored in many other areas of the body including the salivary glands, cerebrospinal fluid and the brain, gastric mucosa, choroid plexus, breasts, ovaries and the ciliary body of the eye. In the brain, iodine concentrates in the substantia nigra, an area of the brain that has been associated with Parkinson's disease."
-------------

I'm not smart enough to swear that all that is true or not. Just throwing it out there for consideration.

Love, Shirley
When the eagles are silent, the parrots begin to jabber"
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Post by garina »

Wow, Tex, I knew low thyroid can cause lots of problems, but I had no idea how much. I, too, am having so many problems (being hypothyroid for 50 years) with finding someone (endo) who is qualified to understand that all thyroid tests are needed for a proper evaluation; i.e., T3 free, T4 free, TSH. Since we moved here almost three years ago, I have not had a thorough thyroid test yet, and have gone to numerous docs for that very purpose.

I also have osteoporosis, so it is hard to regulate the proper amount of thyroid so that my osteoporosis doesn't get worse. Everything is a guess.

I am currently on Synthroid and Cytomel, yet, no doctor here that I have gone to thinks it necessary to take a T3 free test???? I was put on Cytomel before we moved here. My goal is to try Armour.

I certainly understand the eyebrow issue having none at the outer part of mine, also. I will continue my search for an endo that understands these issues, and I also like the idea of an iodine test, which I have never had to my knowledge. I always get a copy of all my labs and have done that for many years now, and I've never noticed an iodine test.

This is a great post, very informative, and you sound like you're on top of these issues.

Thanks for enlightening us.

garina
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Post by dgshelton »

Tex - I know I feel the best when my TSH is between .5 and 1. As far as I know, my endo has never checked my free T3 and free T4. She is of the "old" school that TSH is all that matters. If I asked her to check it, I'm sure she would. When I was having the severe D my TSH went up to 3.4, which is the upper end of the scale that she uses. She assumed it was because I wasn't absorbing it. My last TSH a couple of weeks ago was 1.25. A little higher than I like, but better than 3.4. My endo is really good about taking symptoms into consideration even when the labs are normal.

I find it interesting that my husband has always had a low heart rate, in the low 60's and low blood pressure, considering he is about 80 pounds overweight and never exercises. Sometimes I wish his was higher because he thinks that everything is fine. I worry that he is going to have a heart attack because of the way he eats. I don't know if he's ever had his thyroid checked. He has a yearly check-up and is always told to lose weight, but it falls on deaf ears because he thinks his heart is in excellent health. His cholesterol and triglyceride levels are always high. Hmmm, now I'm worried that maybe his heart rate and blood pressure are artificially low because of hypothyroid problems.

Hugs,
Denise

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Post by tex »

Marliss,

It's amazing how many doctors have weird ideas about Armour. They claim that it's obsolete, and that the dosage is not as accurate as synthetic thyroid supplements, and yet tests show that Armour is almost always more accurately metered, than most synthetic options. Some insurance companies won't pay for it, for a patient past 60 years of age, because they claim that it might be risky for patients with hidden cardiac issues, (which may well be true, but that's age discrimination, since other age groups also carry a risk of hidden cardiac issues). I find it rather hard to believe that synthetic thyroid hormone supplements are without risk. :roll:

My doctor seems to have no qualms about prescribing it. I noticed that the last renewal, (in May), allowed 98 refills of 30 each, before next May. :roll: I've picked up 3 refills, so far. I'm going to have trouble using all 98 refills, obviously. :lol: My dosage is currently 60 mg, so my doc and I are probably going to be considering an increase, the next time I see him. 60 mg is a relatively low dose - it's available in tablets up to 300 mg.


Shirley,

You had me going for a while, there, especially the part about iodine being concentrated in the substantia nigra, (since, as you know, I was once diagnosed with Parkinson's), and I use sea salt, and I'm aware that sea salt is not enriched with iodine the way that iodized table salt is. :shock: :sweat: I checked my multivitamin, though, and it supplies the RDA, (150 mcg), so I should be OK, there.

Thanks.


Garina,

I agree - I find it amazing that even though T3 is the form of thyroid hormone that really counts, (the active form), most doctors try to completely ignore it. :shrug:

Previously, Forest Pharmaceuticals, (the manufacturer of Armour), used to maintain a searchable database of doctors who were willing to prescribe Armour, (and I noticed that my doctor was one of the few in this area who were on the list), but unfortunately, they're in the process of updating their website, so that database is unavailable. :sigh:

You're most welcome. Remember, I'm a patient - not a doctor.

Tex
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Post by tex »

Denise,

That's why I accepted my last thyroid test results without question, because at 1.105, my TSH was as close to what I consider to be "ideal", (between 0.5 and 1.0), as it's ever been.

I don't know about synthetic thyroid supplements, but Armour can be used sublingually, - that is, the tabs can be dissolved under the tongue, to enter the bloodstream faster, and to completely bypass any malabsorption issues. You might ask your doctor about this, or look it up. Of course, the "faster" part will be moot for thyroid supplements that don't contain T3, since it may take days for the body to convert T4 to T3.

Are you aware that it's common for Olympic-class athletes to have resting heart rates in the 32 -38 bpm range, and even lower, in some cases? Their hearts are enlarged, so they pump much more blood per cycle, allowing them to operate at a much slower rate. That heart rate may be normal for your husband, and he may just be lucky to have low BP. :shrug: Still, it wouldn't hurt to have his thyroid numbers checked, just to be on the safe side.

Hugs,
Tex
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Post by dgshelton »

Tex - I actually had an EKG done one time before having surgery and my heart rate was 40. The technician called in a doctor because of bradycardia. He asked if I exercised a lot. At the time I was running between 3 and 5 miles a day. He said, well that's it, you're just in tip top shape. My husband is no where close to being an Olympian athlete! LOL He is the most unathletic person I know. He tells me all the time that he's just lucky to have a low heart rate and blood pressure.

Hugs,
Denise

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Post by tex »

That doctor was right - you were definitely in tip-top shape. That explains your husband's "athletic" test results - he must get them vicariously, from you. :lol:

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Tex
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Post by sarkin »

Ooh, I can't wait for some vicarious fitness to kick in for me!
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Post by dgshelton »

That was around 15 years ago! I can barely walk a mile without wheezing these days! :lol:

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Denise

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