Lesley - About Your Hyponatremia And Elevated BP

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tex
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Lesley - About Your Hyponatremia And Elevated BP

Post by tex »

Hi Lesley,

I finally tracked down the likely cause of your natremia - it's almost certainly caused by the Effexor that you're taking.
Hyponatremia may occur as a result of treatment with SSRIs and SNRIs, including Effexor XR. In many cases, this hyponatremia appears to be the result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Cases with serum sodium lower than 110 mmol/L have been reported. Elderly patients may be at greater risk of developing hyponatremia with SSRIs and SNRIs. Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk (see PRECAUTIONS, Geriatric Use). Discontinuation of Effexor XR should be considered in patients with symptomatic hyponatremia and appropriate medical intervention should be instituted.

Signs and symptoms of hyponatremia include headache, difficulty concentrating, memory impairment, confusion, weakness, and unsteadiness, which may lead to falls. Signs and symptoms associated with more severe and/or acute cases have included hallucination, syncope, seizure, coma, respiratory arrest, and death.
Also, 4% of patients taking Effexor in trials, developed hypertension, which, I believe, you also mentioned as being a problem.

http://www.drugs.com/pro/effexor-xr.html

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Lesley
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Post by Lesley »

WOW! All the symptoms fit! Every single one, including falling though part of the falling is because of my back and leg. If I don't concentrate (and concentration IS a problem) I don't lift it up enough (feels like it weighs a couple of tons) I trip and fall.
You are incredible Tex! What a researcher.

I will send this to my doc and ask her to help me get off it. And I have to get off Nortryptilin also. Maybe, in my old age, I will get healthy. Wouldn't that be a turn out for the books?

Still struggling with going cold turkey on PPIs. Gabes' solution last a couple of hours, but I have to do it 3 times a day at least to be marginally comfortable.

Thanks again Tex!
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Post by tex »

You're most welcome,
Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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