Visit the Microscopic Colitis Foundation Website
Last week I went for a colonoscopy and gastroscopy, my sister has Ulcerative colitis, so they were checking for that and crohns. I began eating gluten again a week prior as per nurses suggestion so they could do a celiac test. GI said at the time that macroscopically everything was perfect, but he took a lot of biopsies. When the biopsies came back, all were normal except for those taken from the colon and ileum. This is what the report says:
TI and Colon Bx: Sections showed fragments of large bowel mucosa with increased numbers of mixed chronic inflammatory cells and eosinophils in the lamina propria together with occasional neutrophils. This is associated with increased lymphocyte transmigration across surface epithelium and crypt epithelium. The subepithelial collagen table is of normal thickness. No epithelial dysplasia or neoplasia. The ileal mucosa shows similar features with some mild villus blunting, increased lymphocyte transmigration across surface epithelium and increased mixed inflammatory cells in the lamina propria. No ulcers, granulomas, viral inclusions or parasites seen.
Comment: Differential diagnosis includes lymphocytic colitis, resolving infective disorder, early stage collagenous collitis and a drug reaction. Occasionally, idiopathic inflammatory bowel disease may show lymphocytosis. While similar features may be seen with coeliac disease it is noted the duodenal biopsy is within normal limits.
I was unable to discuss this report with the GI who performed the procedure, as he does not have an appointment available for me until October. The one thing he did say at the time of the procedure was I was wasting my time going GF and that I did not have any food intolerances and should not be excluding any food groups from my diet - indicating that this was the reason for my weight loss :( So I went back to my GP. He brushed off the microscopic colitis idea, saying it was of no importance, and said there was nothing specific to explain my symptoms. As things had temporarily settled down at this point after the colonoscopy, he sent me on my way with absolutely no treatment/management suggestions. However my symptoms are back in full force, including yellow foamy diarrheah amongst the watery movements, and the general feeling of unwellness and queasiness. My other concern is that 3 weeks prior to the sudden appearance of these symptoms, I started taking Zoloft for anxiety/depression. Since developing the chronic diarrhea I have read that Sertraline is linked to microscopic colitis (noone told me at the time) however my GP refuses to consider that the sertraline is responsible for or at least triggering my symptoms. He doesn't seem to feel my chronic diarrhea is of any importance, but I feel like I shouldn't be expected to just "live with it"!
So what do I do now?
Would appreciate your input. Sorry for the long post.
to the family.
- if I can cheat and just be told what I can and can't eat I'll take that route! But I am sceptical by nature and always like to know the exact science and proof behind a diagnosis and it's treatment etc. I'm not one to believe everything the local quack or naturopath tells me. 
He said give it a couple of weeks on nothing, then go on a different SSRI - he suggested cymbalta or pristique, I don't know anything about them yet. He didn't offer any steroids or other treatments. In fact, he still doesn't say I have a diagnosis of LC, the best he could manage was that I "might have had a little bit of colitis". I suprised he didn't choke as he said that! 