HLA-B27 rheumatoid arthritis

Lilja · Post by **Lilja** » Wed Sep 16, 2015 2:37 am

Hi all,

I suspected that my pains in the lower back, buttocks, hips, legs and feet might be due to a rheumatoid arthritis problem, so I ordered a HLA-B27 test to see if this was an autoimmune issue. This came back negative.

Parallell to this I made an appointment with a rheumatologist (due in December). Now, I wonder: Is there any point in seeing a rheumatologist for RA when the HLA-B27 test is negative? Are there reliable tests of finding out if I have osteoarthritis?

My pains have gotten a lot better, in fact I can be painfree for several days in a row, but they suddenly come back, which puzzles me.

Could the pain be a food reaction? I eat the same diet as I have for the last 15 months; GF, DF, SF and Eggfree. I have had no food accidents, that I know of.

I take magnesium 100% chelated from Doctor's Best (200 mg/day), and vitamin D3 Jarrow Formulas Cholecalciferol (10.000 I.U./day). Maybe this is too much, and that my reservoirs are filled up?

Can you get pains from TOO much magnesium and/or vitamin D3?

Grateful for any suggestions

Lilia

Jonas · Post by **Jonas** » Wed Sep 16, 2015 5:25 am

Hi Lilia,

I have similar problems with arthritis pain in back and hips, and are also HLA-B27 negative. All x-rays, MRI scans are good. But I still have pain more or less every day.
You arthritis symptoms could be due to psoriasis or it could be because you have IBD. You cannot know since there is no test for it.
I’m pretty sure that it is gut related, if your gut is better you get probably less pain. It hard to say if you react to food, stress, (weather), lack of quality sleep or any other factors.
We are all different, so my best advice is to use a diary to see if you can find any patterns. For me sleep is important, and not to exercise too much.

Jonas

sonja · Post by **sonja** » Wed Sep 16, 2015 5:35 am

Hi Ilja,

You have the same problem as I have.
Are you male or female?
I just posted questions about this subject under the entocort poll.
I don't know what the HLA-B27 test is.
I have a problem with osteoartritis and joint pains.The reuma bloodtest was negative.
The reumatologist says that I just have to live with it....(I left him).
next week I see my gut doctor and discuss it with him.
I don't think you take to much magnesium, I take 400 mg magnesium a day and a lot of members do that, I think.
Tex knows evrything about magnesium and D3. (I take 1.000 ie. )

Sonja

Lilja · Post by **Lilja** » Wed Sep 16, 2015 6:07 am

Hi Jonas,
I do have psoriasis, though I don't have any spots now that I have changed my diet. But, since it is autoimmune, the psoriasis is still there. I had an acute trauma 2 years ago, where I was kicked in my back & thighs and beaten severly. So, wheter it is arthritis or injuries that have to heal, I'm not sure. But, at least I wanted to rule out the possibility of HLA-B27.

I did keep a diary some 7 months ago, but I couldn't detect any pattern or direct causes. It's a detective work...

Hi Sonja,
I'm female. Rheumatorid arthritis is an autoimmune disease, as is psoriasis. Why it can be detected through a blood sample, I'm not quite sure.

https://labtestsonline.org/understandin ... /tab/test/

I was hoping that the pain was due to 12 months' use of Entocort, which I stopped in June this year, and that the pain would disappear as soon as the corticosteroids were totally out of my body. One can only hope for one or the other

Lilia

Post by **tex** » Wed Sep 16, 2015 9:09 am

Lilia,

About 80 % of RA patients show positive results on a rheumatoid factor (RF) blood test. This is the one that Sonja referred to. That test would give you some more information to consider, because if it is positive, you probably have RA. But on the other hand, a negative result does not necessarily rule out RA.

Lilia wrote:Can you get pains from TOO much magnesium and/or vitamin D3?

About the only ways that you can get too much magnesium are if you take massive doses for a while, or you take too much and your kidneys are not working correctly. Otherwise, any excess magnesium in the diet is removed by the kidneys.

Regarding vitamin D — it's impossible to get too much vitamin D from sunlight exposure, but it is possible to get too much vitamin D from supplements. Most overdose cases involve daily doses of around 40,000 IU per day or more, for months. When testing vitamin D levels, anything above 100 ng/mL (which is equivalent to 250 nmol/L) is considered to be above the normal range, but not necessarily dangerous, until the level climbs above about 150 ng/mL (which is equivalent to about 375 nmol/L). Above this level, overdose symptoms can develop.

Tex

Lilja · Post by **Lilja** » Wed Sep 16, 2015 11:30 am

I choose to look at it from the positive side for now. Since my HLA-B27 came back negative, I take it as a definite answer for the time being. However, if these pains continue and do not subside for the next 2-3 months, I will have to look into other reasons for of the pains.

The fact that I'm experiencing less pains as time goes by, I lean to thinking that the pains are not AI-induced. The main motivation for being openminded is that I dread surgery. I live alone, on 3rd floor and without elevator, 3-6 weeks on cruches scares me. My sons are busy carreer-hunters with their own families, so I don't want to be a burden to them. But, my MRIs will probably tell the truth, and they have not been sent from the X-ray studio yet, due to a misunderstanding.

Lilia

Jonas · Post by **Jonas** » Fri Sep 18, 2015 2:47 am

I also have psoriasis, have had it for 26 years. And I don't have any spots anymore, have not had any for the last 3 years.

Before I had arthritis and (bad) gut problems, I had psoriasis spots. But now it feels as if the immune system is busy with the gut and arthritis that perhaps the skin is not as interesting to attack anymore. Can not attack everything at once

It could be the exclusion of dairy (in my case) that made the skin better. Again, who knows?

Lilja · Post by **Lilja** » Fri Sep 18, 2015 5:25 am

Jonas wrote:I also have psoriasis, have had it for 26 years. And I don't have any spots anymore, have not had any for the last 3 years.

Before I had arthritis and (bad) gut problems, I had psoriasis spots. But now it feels as if the immune system is busy with the gut and arthritis that perhaps the skin is not as interesting to attack anymore. Can not attack everything at once

It could be the exclusion of dairy (in my case) that made the skin better. Again, who knows?

Hei Jonas,
I agree with you. When going GF and DF free, my psoriasis spots disappeared. But there is also something called psoriasis arthritis, and this came into full blossom instead. Maybe the immune system can only work on one thing at a time, and we finally can get rid of all issues? One can only hope

Lilia