Visit the Microscopic Colitis Foundation Website
Here's a link to a fracture risk assessment tool:
http://www.shef.ac.uk/FRAX/tool.jsp?locationValue=9.
It factors in glucocorticoid use and secondary osteoporosis, which would be osteoporosis due to having a condition such as an IBD. The link is for the US (inches and pounds), but you can click on the "Calculation Tool" link if you're from another country. It looks like the site is located in the UK.
You might also be interested in this article from the New York Times titled "Drugs to Build Bones May Weaken Them," located here:
http://www.nytimes.com/2008/07/15/healt ... wanted=all
Gloria
Osteoporosis Fracture Risk Assessment Tool
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Osteoporosis Fracture Risk Assessment Tool
You never know what you can do until you have to do it.
I'm really in a quandry. I took the FRAX test. When I checked that I'm taking a glucocorticoid, my risk of fracture in the next 10 years was 25%, a pretty high number. After checking "no" for the glucocorticoid, my risk is cut to 12%, still a pretty high number according to the article. The test doesn't distinguish between type or quantity of glucocorticoids taken, however.
The risk appears to rise for those who are on Fosamax for 5 years or more and it doesn't seem to affect everyone. Maybe the solution is to take it for a few years, then go off it for a time, which is pretty much what I've done. Nonetheless, I had significant deterioration in 6 years.
I need to schedule another bone density test. It's been 3 1/2 years since my last one. I'm a little nervous about what it will show.
Gloria
The risk appears to rise for those who are on Fosamax for 5 years or more and it doesn't seem to affect everyone. Maybe the solution is to take it for a few years, then go off it for a time, which is pretty much what I've done. Nonetheless, I had significant deterioration in 6 years.
I need to schedule another bone density test. It's been 3 1/2 years since my last one. I'm a little nervous about what it will show.
Gloria
You never know what you can do until you have to do it.
Gloria, the sooner you get the test the sooner you can start making some decisions. That's an obvious statement and I've certainly procrastinated enough in my own life but I do like knowing just where I stand. 
By the way, my risk was 11% for a major osteoporotic fracture. Hip fracture 1.1% Not that that helps any. I really didn't think I checked anything that would make me high risk (except for my age) unless being overweight counts.
Take care.......
Love, Shirley
By the way, my risk was 11% for a major osteoporotic fracture. Hip fracture 1.1% Not that that helps any. I really didn't think I checked anything that would make me high risk (except for my age) unless being overweight counts.
Take care.......
Love, Shirley
When the eagles are silent, the parrots begin to jabber"
-- Winston Churchill
-- Winston Churchill
Gloria,
It's almost certain that the glucocorticoid influence in that analysis, is considered to be the maximum effect of a full, normal dose of prednisone. IMO, that wouldn't really apply to your situation, since only about 10% of a budesonide treatment is normally absorbed into the bloodstream, and you're only taking a fraction of a normal dose, besides.
The engineering training in me tells me that those fractures that are typical of long-term treatment with bisphosphonates, are due to extreme embrittlement at the surface, resulting in cracks that are bound to propagate, and eventually cause a brittle failure. It's almost as of the drugs kill the surface of the bone. The fact that the cracks are there in the first place, indicate that the surface of the bone is extremely brittle, (and since those cracks are unique to patients treated with these drugs, then it's pretty clear that drugs are causing the cracks. Not only should the cracks not be there in the first place, but obviously the drugs interfere with the body's ability to repair the damage. If we were talking about this happening in a structure, or a machine, no engineer could afford to approve a design that would allow this to occur. It would be an accident waiting to happen.
Tex
It's almost certain that the glucocorticoid influence in that analysis, is considered to be the maximum effect of a full, normal dose of prednisone. IMO, that wouldn't really apply to your situation, since only about 10% of a budesonide treatment is normally absorbed into the bloodstream, and you're only taking a fraction of a normal dose, besides.
The engineering training in me tells me that those fractures that are typical of long-term treatment with bisphosphonates, are due to extreme embrittlement at the surface, resulting in cracks that are bound to propagate, and eventually cause a brittle failure. It's almost as of the drugs kill the surface of the bone. The fact that the cracks are there in the first place, indicate that the surface of the bone is extremely brittle, (and since those cracks are unique to patients treated with these drugs, then it's pretty clear that drugs are causing the cracks. Not only should the cracks not be there in the first place, but obviously the drugs interfere with the body's ability to repair the damage. If we were talking about this happening in a structure, or a machine, no engineer could afford to approve a design that would allow this to occur. It would be an accident waiting to happen.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
I fairly recently started to take curcumin (turmeric extract) to try and keep my MGUS from progressing.
Circumin is anti-inflammatory, so logically it may help in MC too, although I haven't spotted any research on that yet.
It also has a positive impact on bone density.
If you are concerned about your bone density, you might want to investigate this. I've included some links to a blogger who has multiple myeloma (which destroys bone) and has done a lot of study into this. Her personal results are encouraging. It could be a way to offset the negative impact of the drugs.
http://margaret.healthblogs.org/2008/12 ... t-results/
http://margaret.healthblogs.org/life-wi ... bone-loss/
I know it is rude to brag, but my DEXA T-score came back positive, which was a bright spark in some otherwise depressing test results.
Lyn
Circumin is anti-inflammatory, so logically it may help in MC too, although I haven't spotted any research on that yet.
It also has a positive impact on bone density.
If you are concerned about your bone density, you might want to investigate this. I've included some links to a blogger who has multiple myeloma (which destroys bone) and has done a lot of study into this. Her personal results are encouraging. It could be a way to offset the negative impact of the drugs.
http://margaret.healthblogs.org/2008/12 ... t-results/
http://margaret.healthblogs.org/life-wi ... bone-loss/
I know it is rude to brag, but my DEXA T-score came back positive, which was a bright spark in some otherwise depressing test results.
Lyn
Thank you for the links, Lyn. I'll have to investigate the curcumin treatment. Oddly enough, the recipe for the bread I'm eating includes tumeric. I had no idea why other than perhaps to make the color slightly yellow.
I'm very happy that your DEXA T-score was positive. We love to celebrate success here. Congratulations!
Gloria
I'm very happy that your DEXA T-score was positive. We love to celebrate success here. Congratulations!
Gloria
You never know what you can do until you have to do it.
Lyn,
Here are some links to abstracts of research articles showing that curcumin is an effective treatment for helping to maintaining remission of ulcerative colitis, and I can see no reason why it wouldn't be beneficial for MC, also.
http://findarticles.com/p/articles/mi_m ... _n19170706
http://www.ncbi.nlm.nih.gov/pubmed/15793857
http://ajpgi.physiology.org/cgi/content ... 365.2008v1
Never hesitate to post about good test results. Heck, as Gloria said, we're always glad to see good results around here.
Tex
Here are some links to abstracts of research articles showing that curcumin is an effective treatment for helping to maintaining remission of ulcerative colitis, and I can see no reason why it wouldn't be beneficial for MC, also.
http://findarticles.com/p/articles/mi_m ... _n19170706
http://www.ncbi.nlm.nih.gov/pubmed/15793857
http://ajpgi.physiology.org/cgi/content ... 365.2008v1
Never hesitate to post about good test results. Heck, as Gloria said, we're always glad to see good results around here.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
I know Fosomax & Actonel are out!
I use Miacalcin nasal spray.
http://www.everydayhealth.com/crohns-di ... h_20090218
I use Miacalcin nasal spray.
http://www.everydayhealth.com/crohns-di ... h_20090218
"What the heart gives away is never gone ... It is kept in the hearts of others."
Dee,
I've never heard of Miacalcin nasal spray. I did a search on it and it has it's own side effects, including diarrhea.
Have you had any of the listed side effects? I always worry about nasal applications like Zicam because I'm afraid I'll lose my sense of smell. Poor Barbara has lost hers.
BTW, I had my bone density test done today. Results will be available on Monday.
Gloria
I've never heard of Miacalcin nasal spray. I did a search on it and it has it's own side effects, including diarrhea.
Have you had any of the listed side effects? I always worry about nasal applications like Zicam because I'm afraid I'll lose my sense of smell. Poor Barbara has lost hers.BTW, I had my bone density test done today. Results will be available on Monday.
Gloria
You never know what you can do until you have to do it.
Lyn, if you feel it would be appropriate, you can share this with the blogger. I got it from another forum.
http://www.npr.org/templates/story/stor ... d=99970093
http://www.npr.org/templates/story/stor ... d=99970093
DISCLAIMER: I am not a doctor and don't play one on TV.
LDN July 18, 2014
Joan
LDN July 18, 2014
Joan