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Gluten, dairy, IBS triggers!
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Gluten, dairy, IBS triggers!
DISCLAIMER: I am not a doctor and don't play one on TV.
LDN July 18, 2014
Joan
LDN July 18, 2014
Joan
Joan,
Great find!
By checking out the reference in that article, and following a couple of leads, I found the following two articles. The first one is the one that Dr. Briffa mentioned in his article, and it suggests that what we have been waiting for, and searching for, for years - proof of Non-Celiac Gluten Sensitivity, (NCGS), may be right around the corner. At least researchers are now discussing it, and proposing research projects to investigate it. Maybe mainstream medical research will finally come around, and acknowledge the huge error that doctors have been making in their assumptions, when they deny the spectrum of gluten sensitivity. The second link references an article connected with research involving the lead author of the first article, that demonstrates how bacterial antigens can affect the function of the tight junctions, (presumably, to induce the leaky gut syndrome, though they don't refer to it that way), resulting in the potential for heightened sensitivity to gluten. Though the article references IBS, only, it's pretty obvious that this would also apply to the IBDs, including MC.
In fact, if I read that article correctly, this could be the missing link that validates MC as an autoimmune disease, by demonstrating that intestinal bacteria are indeed the target of the inflammatory response generated by the immune system. I suspect that the researchers don't even realize the full significance of what they have found.
http://www.ncbi.nlm.nih.gov/pubmed/19455131
http://www.pubmedcentral.nih.gov/articl ... id=2715133
It's interesting that they decided to "test the waters", by publishing a proposal of the idea, (in the first article), before actually tackling the research. Maybe they're just "trolling" for a sponsor, but a paying sponsor may be hard to find, since Big Pharma is not likely to be interested in such a project, (unless they are banking on future sales of anti-zonulin pills, or special enzymes to target gluten). At any rate, publishing discussions about the concept, is definitely progress, and hopefully it's the first step toward resolving the issue, (something that is long overdue). This just goes to show how hard it is to overcome incorrect assumptions in science. After they've been around as long as this one has, too many people, (who should know better), consider them to be fact.
Thanks for posting that link.
Tex
Great find!
By checking out the reference in that article, and following a couple of leads, I found the following two articles. The first one is the one that Dr. Briffa mentioned in his article, and it suggests that what we have been waiting for, and searching for, for years - proof of Non-Celiac Gluten Sensitivity, (NCGS), may be right around the corner. At least researchers are now discussing it, and proposing research projects to investigate it. Maybe mainstream medical research will finally come around, and acknowledge the huge error that doctors have been making in their assumptions, when they deny the spectrum of gluten sensitivity. The second link references an article connected with research involving the lead author of the first article, that demonstrates how bacterial antigens can affect the function of the tight junctions, (presumably, to induce the leaky gut syndrome, though they don't refer to it that way), resulting in the potential for heightened sensitivity to gluten. Though the article references IBS, only, it's pretty obvious that this would also apply to the IBDs, including MC.
In fact, if I read that article correctly, this could be the missing link that validates MC as an autoimmune disease, by demonstrating that intestinal bacteria are indeed the target of the inflammatory response generated by the immune system. I suspect that the researchers don't even realize the full significance of what they have found.
http://www.ncbi.nlm.nih.gov/pubmed/19455131
http://www.pubmedcentral.nih.gov/articl ... id=2715133
It's interesting that they decided to "test the waters", by publishing a proposal of the idea, (in the first article), before actually tackling the research. Maybe they're just "trolling" for a sponsor, but a paying sponsor may be hard to find, since Big Pharma is not likely to be interested in such a project, (unless they are banking on future sales of anti-zonulin pills, or special enzymes to target gluten). At any rate, publishing discussions about the concept, is definitely progress, and hopefully it's the first step toward resolving the issue, (something that is long overdue). This just goes to show how hard it is to overcome incorrect assumptions in science. After they've been around as long as this one has, too many people, (who should know better), consider them to be fact.
Thanks for posting that link.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Good luck with that project.Joan wrote:One of these days, if I live that long, she'll believe in EnteroLab.
You're most welcome.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.