LDN Research Trust

angy · Post by **angy** » Fri Apr 23, 2010 5:54 am

Went to see my gi doc lately and picked up an information leaflet regarding treatment with LDN which is committed to trials in the treatment for autoimmune disease...Although the list below may not necessarily include mc in the titles but it appears that this form of disease is included in these trials...The trust is originated in uk but it also has a base in the usa. Here are some links...

http://www.ldnresearchtrust.org/

http://www.lowdosenaltrexone.org/ldn_and_ai.htm

http://www.lowdosenaltrexone.org/index.htm

LDN and Autoimmune DiseaseLow-dose Naltrexone (LDN)

In Brief

There is growing recognition in the scientific community that autoimmune diseases result from immunodeficiency, which disturbs the ability of the immune system to distinguish "self" from "non-self". The normalization of the immune system induced by LDN makes it an obvious candidate for a treatment plan in such diseases.

The experience of people who have autoimmune diseases and who have begun LDN treatment has been remarkable. Patients with diagnoses such as systemic lupus, rheumatoid arthritis, Behcet's syndrome, Wegener's granulomatosis, bullous pemphigoid, psoriasis, and Crohn's disease have all benefited.

Because LDN clearly halts progression in multiple sclerosis, its use has been more recently extended to other neurodegenerative diseases, such as Parkinson's disease and amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) whose etiology remains unknown but for which there is suggestive evidence of a possible autoimmune mechanism.

In addition, people with fibromyalgia and chronic fatigue syndrome have had marked improvement using LDN, suggesting that these entities probably have an important autoimmune dynamic as well.

> Bernard Bihari, MD, as well as other physicians and researchers, have described beneficial effects of LDN on a variety of diseases:

Cancers:
Bladder Cancer
Breast Cancer
Carcinoid
Colon & Rectal Cancer
Glioblastoma
Liver Cancer
Lung Cancer (Non-Small Cell)
Lymphocytic Leukemia (chronic)
Lymphoma (Hodgkin's and Non-Hodgkin's)
Malignant Melanoma
Multiple Myeloma
Neuroblastoma
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer (untreated)
Renal Cell Carcinoma
Throat Cancer
Uterine Cancer
ALS (Lou Gehrig's Disease)
Alzheimer's Disease
Ankylosing Spondylitis
Autism Spectrum Disorders
Behcet's Disease
Celiac Disease
Chronic Fatigue Syndrome
CREST syndrome
Crohn's Disease
Emphysema (COPD)
Endometriosis
Fibromyalgia
HIV/AIDS
Irritable Bowel Syndrome (IBS)
Multiple Sclerosis (MS)
Parkinson's Disease
Pemphigoid
Primary Lateral Sclerosis (PLS)
Psoriasis
Rheumatoid Arthritis
Sarcoidosis
Scleroderma
Stiff Person Syndrome (SPS)
Systemic Lupus (SLE)
Transverse Myelitis
Ulcerative Colitis
Wegener's Granulomatosis

Post by **tex** » Fri Apr 23, 2010 7:48 am

Ye, we've had discussions about LDN before, and frankly, I'm surprised that as far as I can recall, only one member has actually tried it, and she doesn't post. I'm guessing that LDN treatment is overlooked, mostly because doctor's never suggest it, (it requires a prescription).

Are you considering signing up?

Tex

grannyh · Post by **grannyh** » Fri Apr 23, 2010 8:46 am

Hope if you sign up you will post about the results.
grannyh

Stanz · Post by **Stanz** » Fri Apr 23, 2010 9:36 am

Angy,

I considered taking this after my initial dx, it sounds like a very promising drug and there are quite a few blogs, etc. where people talk about their personal experience with it. It is a drug that needs to be monitored and as I was going to be out of town for a month, my ND and I decided to just go with the L-Glutamine initially. The Glutamine worked just great for me, so I never needed to go the LDN route, but from all my research, it would have been the second option I tried. If I remember correctly, it's also inexpensive, which can explain why our MD's don't prescribe it.

angy · Post by **angy** » Fri Apr 23, 2010 10:37 am

Yes guys i am thinking about signing up for that trial..and if i do i will update on the board

Im thinking that it may only be available to those who have failed with other meds...considering i dont take asacole on a regular basis..., i stopped it but only take with the ocassional bad flare...i have found that aloe vera juice (high potency) has helped with flares very well...

But then again the actual LDN institute may help me get on to the trials, but as tex said its got to be approved by your gp or consultant...

Stanz thats interesting about L-Glutamine, i havent tried that ...maybe i should..

Stanz · Post by **Stanz** » Fri Apr 23, 2010 11:11 am

Angy,

I posted my original protocol here: http://www.perskyfarms.com/phpBB2/viewt ... ght=#68897

My D and nearly all symptoms were gone w/in 3 weeks. I have had very few days where I've had any symptoms other than some gas and a touch of D that never lasted more than a day and was the result of being glutened. I think it has been frankly miraculous and I would love to see someone else try it.

I no longer use immodium and I do only 1 T. of the Glutamine now, have been doing that for the last month. I only take 1 ProBoulardi and have increased my Vit D3 to 3/day and also take sublingual B6, Folic Acid and B12. I don't do the coconut oil anymore either. I have been GF since August. I don't seem to have any other food sensitivities. I am a double DQB1, my Enterolab tests are also posted on this forum.

Connie

grannyh · Post by **grannyh** » Fri Apr 23, 2010 11:53 am

I just had massive dental work and will be taking tylenol with codeine from what I have read LDN would make the codeine not work. Wonder what they use for pain on LDN??
grannyh

angy · Post by **angy** » Fri Apr 23, 2010 12:24 pm

thanks for sharing that thread and link stanz... im pleased you are well...
Im worried about the ldn then, cos i take cocodomol for migraine mmm!!!

angy · Post by **angy** » Thu Apr 29, 2010 4:03 pm

interesting videos on u tube regarding LDN treatment and autoimmune disease....several videos here...

heres the link

http://www.youtube.com/user/TheLDNresea ... RI5f69N2eo

angy · Post by **angy** » Sun Jun 06, 2010 5:34 pm

linda you might like to look at these links..in the first thread...or maybe you have already...

Linda in BC · Post by **Linda in BC** » Mon Jun 07, 2010 10:57 am

Thanks, Angie, and yes, I have spent a lot of time on the LDN.org website and many, many others. There is actually a ton of information out there, although very little on it regarding digestive disorders ( except Crohn's ) and nothing on it and MC. Are you still thinking of trying it?
Linda