New Antibiotic for IBS shows promise

Zizzle · Post by **Zizzle** » Fri Jan 07, 2011 10:30 am

Other than the high price ($20+ per pill), the new antibiotic being tested for IBS looks interesting, primarily because it acts on the gut, much like Endocort versus Prednisone. I would try it if given the opportunity, especially since results lasted for 8 weeks following the initial treatment. 41% of patients reported adequate resolution to their symptoms, compared to 32% on placebo, so maybe it's not that effective for everyone. But for those of us who suspect baterial overgrowth/imbalance, and who generally improve on other antibiotics, this may just work. Hopefully it addresses a cause of our MC, not just the symptoms, even if only temporarily.

http://news.yahoo.com/s/ap/20110105/ap_ ... bowel_drug

Maybe I'll reach out and suggest they do a clinical trial on MC, not just IBS!

Post by **tex** » Fri Jan 07, 2011 12:57 pm

Interesting, but why not just use the placebo? It's much safer than the antibiotic treatment, and fully 78% as effective. That's pretty doggone good efficacy for a placebo, but the main reason why it looks so good compared with the antibiotic, is simply because the antibiotic has such a low efficacy rate, to begin with.

Remember the following thread? Research shows that IBS sufferers respond well to placebos, even when they know beforehand that they're taking a placebo.

http://www.perskyfarms.com/phpBB2/viewtopic.php?t=12878

Tex

Robbie · Post by **Robbie** » Fri Jan 07, 2011 10:08 pm

That's the antibiotic I was put on by my local doctor a few weeks before I got scoped (took it for ten days around the 3rd of June). I have believed all along that it contributed to the bad flare I went into, which got even worse after the scope was done. I was already bad, but had seen some improvement on my own by making dietary changes (starting with dairy) before I decided to see a doctor.

Too bad it did not cure my "IBS" (the garbage can diagnosis I got from the big city GI doc last November)

JLH · Post by **JLH** » Sat Jan 08, 2011 1:26 pm

My brother tried it for his IBS-c with no success over a year ago.

I still wonder if he has MC even though his last GI did random biopsies. We do have the same parents and I got a sensitivity gene from each of them........

hoosier1 · Post by **hoosier1** » Sat Jan 08, 2011 1:54 pm

I tried this antibiotic per Dr. Pimental's protocol (published) for IBS about 5 years ago. I even read his book cover to cover. Did nothing for me except make me feel worse. But then again, I always felt I had been misdiagnosed with the classic "IBS" label.