CC and LC

Mags · Post by **Mags** » Mon Jan 10, 2011 5:42 pm

How common is it to have both CC and LC? I have looked on the forum trying to answer my own question and I can't seem to find it. I have both. Is it harder to treat both? Is it harder to get into remission?

Sorry if this is a stupid question...

Mags

natythingycolbery · Post by **natythingycolbery** » Mon Jan 10, 2011 5:51 pm

Mags, it isn't a stupid question, I believe there are a few people on the board that have both, and that there are discussion/debates in the medical world into if LC and MC are the same thing but at different stages of development.

I'll see if I can find a link to this for you.

I'm not sure about the treatment/remission thing though so can't help you there.

Katy.

x

natythingycolbery · Post by **natythingycolbery** » Mon Jan 10, 2011 5:57 pm

this is all i can currently find.. http://www.medicinenet.com/lymphocytic_ ... rticle.htm

It says on the second page about half way down...

There are two types of microscopic colitis; lymphocytic colitis and collagenous colitis. In lymphocytic colitis, there is an accumulation of lymphocytes (a type of white blood cell) within the lining of the colon. In collagenous colitis, there is an additional layer of collagen (scar tissue) just below the lining. Some experts believe that lymphocytic colitis and collagenous colitis represent different stages of the same disease.

Pat · Post by **Pat** » Mon Jan 10, 2011 6:19 pm

I have both. Let me know if you find out anything about that. I also have fructose malabsorption.

Pat

Post by **tex** » Mon Jan 10, 2011 7:54 pm

Most people with CC also have some degree of lymphocytic infiltration, (which is the marker for LC), but the pathologist often chooses to diagnose the case as CC, because of the CC marker, (thickened collagen bands in the lamina propria), which is not present with LC. IOW, it's somewhat common to have both markers. However, when both markers are present, many pathologists refer to the diagnosis as simply MC, though many of us also refer to either LC or CC as MC, since the clinical symptoms are the same, and the treatment is the same, regardless of the type.

Actually, there are now at least a dozen different types of MC, which have been documented, to date. The clinical symptoms, and the treatment, is the same for all of them.

Tex

Mags · Post by **Mags** » Mon Jan 10, 2011 8:18 pm

Tex--

Thanks for the reply!

Is there a way for me to get info on all these different types of MC? I was discussing it with my Mom today, and she has several of the problems others have here (MVP, scoliosis, thyroid problems) in addition to a diagnosis of IBS. There is no way she would get on this forum (computers?..argh!), so any info about the different types would be greatly appreciated.

I know if anyone knows, it's you..

Mags

Post by **tex** » Mon Jan 10, 2011 8:51 pm

Hi Mags,

Sure, here is a listing of the other rarely-encountered forms of this disease that I am aware of, and new forms of the disease are still being discovered on a somewhat regular schedule: The variations include MC with giant cells, Paucicellular and Asymptomatic Lymphocytic Colitis, Clear Cell Colitis, (pediatric), MC with granulomatous inflammation, MC not otherwise specified, (NOS), cryptal lymphocytic coloproctitis, and other variations of similar histopathological changes, such as Paneth cell hyperplasia, or epithelial degeneration. Don’t expect your GI specialist to be able to name all the different forms of this disease, though, because more than likely, he or she has never even heard of most of them, except for collagenous colitis, lymphocytic colitis, and the blanket term, microscopic colitis.

Here are some references on the various less-common forms:

http://cat.inist.fr/?aModele=afficheN&cpsidt=17879076

http://lib.bioinfo.pl/pmid:17878641

http://www.medscape.com/viewarticle/487838

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675119/

By the way, we have a running joke on this board about the inability of most GI doc's to adequately treat IBS.

The question:
What is the difference between MC and IBS?

The answer:
A few biopsy samples.

Tex

Mags · Post by **Mags** » Mon Jan 10, 2011 9:40 pm

Tell me about it--how many people do you know that demand and harass their GI for another colonoscopy?!?

Joefnh · Post by **Joefnh** » Mon Jan 10, 2011 9:45 pm

Mags wrote:Tell me about it--how many people do you know that demand and harass their GI for another colonoscopy?!?

Said in Tiny Tim's voice (English accent)...

Please sir, can I have another?

--Joe

Post by **tex** » Mon Jan 10, 2011 9:55 pm

Tex

natythingycolbery · Post by **natythingycolbery** » Tue Jan 11, 2011 3:02 am

joefnh wrote:
Mags wrote:Tell me about it--how many people do you know that demand and harass their GI for another colonoscopy?!?

Said in Tiny Tim's voice (English accent)...

Please sir, can I have another?

--Joe

The english lit half of me has just come out...... are you refering to Oliver Twist or A Christmas Carol there? Or both????

Joefnh · Post by **Joefnh** » Tue Jan 11, 2011 8:53 am

Naty I knew somebody would ask that... I was envisioning the Christmas Carol scene, with a twist. Tiny Tim out on the snowy street talking to a GI doctor...

I know warped

--Joe

natythingycolbery · Post by **natythingycolbery** » Tue Jan 11, 2011 8:58 am

now i have dr who quotes in my head!

Mags · Post by **Mags** » Tue Jan 11, 2011 3:38 pm

Is there a bathroom on the TARDIS?

natythingycolbery · Post by **natythingycolbery** » Tue Jan 11, 2011 4:09 pm

I should hope so!