Possible link mercury with gluten and casein intolerance?

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Linda in BC
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Possible link mercury with gluten and casein intolerance?

Post by Linda in BC »

I was doing a little research tonight and came across this article about a possible connection between mercury toxicity interfering with digestion of gluten and casein. While the article is mainly concerned with autism, it seems to explain and point to a connection between casein and gluten and opioid receptors.
"Mercury and toxic metals block enzymes required to digest milk casein and wheat gluten, resulting in dumping morphine-like substances in the blood"
Anyone ever hear of this idea?

Here is a link to the article: http://www.thenaturalrecoveryplan.com/d ... casein.pdf

It was also interesting because they mentioned Low Dose Naltrexone (LDN) a couple of times.

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JoAnn
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Post by JoAnn »

Hi Linda :smile: Interesting information. How are you doing with your LDN experiment and entocort? Even though I'm in remission, I wonder if LDN might be an insurance policy to prevent future problems???? I'm following your experience with great interest. I also think about Grannyh's great success with long term use of entocort and her ability to eat what she wants. Maybe staying on entocort longer isn't so bad :???: Questions, questions, questions, Love JoAnn
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Post by TooManyHats »

This is well known in the autism community. I have a child with autism, so I have friends who have their children on g/f-c/f diets. One young man I know is DEFINITELY "activated" when he gets hold of anything with gluten or casein. By activated I mean, there is much more typical autistic behavior, i.e. talking to himself, echolalia, and self-stimming. In short, it acts as an opioid. But, this is only for a percentage of individuals with autism. Like cancer, autism is an umbrella term. It's a collection of diseases with many causes that falls under the umbrella term of autism. Some with autism, like my son, are purely genetic and don't have the gastrointestinal components that so many have. But, some are definitely effected by diet. Some children go for Chelation to remove the mercury from their bodies. It works for some--stress SOME. It is believed that some have a genetic component that prevents their bodies from eliminating mercury--just another example of the subtypes of autism. If you are interested in reading more, google the DAN protocol.
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Post by tex »

Linda,

That's a very technical article, and it is probably true that mercury adversely affects the production of the necessary enzymes for digesting gluten and possibly casein. However, the issue is not that simple. While it is true that normally, the human digestive system can break down most of the amino acid chain that comprises gluten, there are numerous amino acid sequences, (peptides), within the gluten chain, for which none of us, (no humans), have the capability to produce the necessary enzymes to further break down those peptides into their individual amino acids, (which is necessary for complete digestion). In fact, there are almost a hundred of these peptides in gluten, (the worst of which is the alpha gliadin peptide), and they are all mostly indigestible - no one can digest them, not even "normal" people. With "normal" people, though, the peptides just pass harmlessly through their digestive system, and their immune system ignores them. People who are gluten-sensitive, however, have a more sensitive immune system, which detects the peptide as a foreign object, and launches a T-cell reaction against it.

Therefore, while mercury contamination might add even more digestive system woes, (by further diminishing the ability to digest gluten), it will have virtually no significant effect on the peptides that we react to, because no one can digest them, anyway. :shrug:

Of course, that's just my opinion, but it is a fact, of course, that no one can digest the peptides in gluten to which we, (and celiacs), react, and mercury has nothing to do with that part of it.

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Post by Linda in BC »

Ahhh.. OK.. thanks for reading the article, Tex, and taking the time to interpret it and point out why it is actually a moot point!
I got to thinking last night about your hypothesis that LDN could cause it's improvement because it suppresses the Opioid receptors ( not because stimulates production after) and the part in this article about how casein acts like an opiate and binds to the receptors. I decided to try a little experiment and ate a couple of small pieces of aged cheddar cheese just before taking my LDN last night. Interestingly , I had no adverse effects from the cheese this morning. (If I could find the "shrug " emoticon I would have put it in here :-)
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Post by tex »

Neurological effects may be more important with MC than we generally realize, (and, of course, they're completely off the radar of mainstream medicine). That's very interesting that the timing, (at least, presumably, the timing was important), of your LDN treatment, (right after eating a source of casein), apparently prevented any reaction to the casein. That suggests that the effects go way beyond the neurological response.

Incidentally, the remarks in the article, referring to the fact that milk with variant A1 of beta-casein, (containing 4 times the casomorphine-7 as A2 milk), are quite correct. Unfortunately, most dairies on this continent use cows with A1 type milk, (primarily Holsteins, which are the worst, as far as A1 content is concerned, but which excel at milk production, as far as production volume is concerned). Guernseys are the best, (most predominantly A2), and Brown Swiss come in second, but it's not easy to find dairies with Guernsey or Brown Swiss cattle these days.

Of course, many of the Old World societies still use A2 type cows, (Guernseys, Brown Swiss, Jerseys, etc.), but it's difficult to say whether people in those countries who are sensitive to casein are any better off than those of us drinking Holstein milk, because the gastrointestinal symptoms will still be just as severe, regardless of the fact that the neurological response might be reduced to only a fourth of the potential that we are exposed to. The problem is, realistically, it's probably difficult for someone to tell the difference between the resulting effects from an A2 opioid dose, and an A1 dose, (with 4 times the concentration). With food sensitivities, once the minimum dose threshold is surpassed, then dose seems to make little difference, if it is increased beyond that. IOW, we seem to generate all sorts of antibody levels, but they seem to have little correlation with the severity of symptoms. I'm guessing that the same result might apply to corresponding neurological events. The bottom line is, while A2 type milk might be less harmful to us, (theoretically speaking), if we are sensitive to casein in the first place, then the difference may become a moot point. :shrug:

Tex
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Post by Polly »

Tex,

Your encyclopedic (or should we now say wikipedic - LOL!) knowledge continues to astound me!!! Thanks for readily and unfailingly using it to help us out.

With love and admiration,

Polly
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Post by Linda in BC »

:iagree:

:bigbighug: for Tex

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Post by tex »

Gosh, thanks. After those kind remarks, I sorta wish I knew what I was talking about. LOL.

Love,
Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by Linda in BC »

Well, you may not completely know what your're talkign about but you know a darn sight more than most of us do! :wink:

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Post by Polly »

Amen.

Love,

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Post by Joefnh »

I can only say I wholeheartedly agree. Tex your knowledge is legendary and encyclopedic... I go by by earlier comment you do need to write a book or go on the lecture circuit.

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Post by tex »

Joe,

You must be clairvoyant. As a matter of fact, for the first time in a long time, I looked up a few references and wrote a couple of paragraphs last night, (for chapter 9). Unfortunately, I haven't finished any of the previous chapters yet, though. :lol: I really do need to make a concerted effort to get it done, one of these days.

Tex
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Post by faithberry »

Tex,

I agree, you knowledge on these topics is amazing. It was very illuminating to read about both topics. That dashes my hopes that A2 milk would be acceptable to the casein-intolerant. That's OK. Far better to know. Thanks for being so generous with you time, knowledge and support.

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Post by Bifcus16 »

I tried A2 milk. Bad result. Won't do that again.

Lyn
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