Feel free to discuss any topic of general interest, so long as nothing you post here is likely to be interpreted as insulting, and/or inflammatory, nor clearly designed to provoke any individual or group. Please be considerate of others feelings, and they will be considerate of yours.
It means there are localized areas with on-going "minor" lymphocytic infiltration both at the surface layer, (the mucosa), and to a lesser degree, in the subsurface layer, (the lamina propria), of the epithelia of the colon. By "minor" I simply mean not severe. "Nonspecific", (in medical terms), means that it is not attributed to any single known cause, which simply means that the sample did not show any obvious reasons for the inflammation, (such as cancer, Crohn's or UC).
Basically, that finding is consistent with a diagnosis of lymphocytic colitis. If the lymphocytic count is barely above normal levels, (for example, in the range of 20-25 lymphocytes per high magnification area), then that might indicate paucicellular lymphocytic colis.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Lisa from what it sounds like it is LC. When the term non-specific is used, it means that is not an extreme case with large numbers infiltrations that might be seen with other disease mechanisms like ulcerative colitis or Crohns. This is the main reason LC and CC is called microscopic colitis.
Did the report happen to mention the count rate of the lymphocytes?
lisa, maybe it is me, but haven't you asked the same question before here and didn't Tex give you the same answer? Or did you already have a new colonoscopy and is this the result of your last one?
If you still have questions, if you really have MC, than go for another colonoscopy.
"As the sense of identity shifts from the imaginary person to your real being as presence awareness, the life of suffering dissolves like mist before the rising sun"
It sort of sounds as though neither your GI specialist nor your pathologist is familiar enough with the disease to feel comfortable making a diagnosis, so they are afraid to commit to anything. Unfortunately, that doesn't help the patient. Please don't let the term "nonspecific" confuse you, because that same term appears in the description for LC/CC/MC in the billing code for LC/CC/MC. Doctors just like to use it, to cover their butts.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.