PPI'S

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nursegirl
Posts: 3
Joined: Sun Aug 08, 2010 7:22 pm

PPI'S

Post by nursegirl »

I have been gluten free for almost seven months. I have MC and Celiacs. Six month follow up blood test done a couple of weeks ago. Celiac panel is now negative. GI doc says I am doing a good job avoiding gluten. Easy for him to say. I have not eaten out or eaten anything not prepared in my home by me or my husband. My question is I am still on Nexium. Should I stop this medicine?. I had a relapes after going gluten free and went back on Entocort for eight weeks. The D returned. Have been on sulfasalazine for last two months and doing pretty good. Some soft to loose stools once in a while but much much better. Could the Nexium be the cause of the stool problem? Any advice would be appreciated.
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tex
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Joined: Tue May 24, 2005 9:00 am
Location: Central Texas

Post by tex »

Hi,

PPIs are definitely a problem for some people. They must be a pretty common problem, because even the Mayo Clinic is aware of it:
Risk factors
By Mayo Clinic staff

Some research studies indicate that using certain medications may increase your risk of collagenous colitis and lymphocytic colitis. But not all studies agree. Medications linked to these conditions include:

* Clozapine (Clozaril)
* Entacapone (Comtan)
* Esomeprazole (Nexium)
* Flutamide
* Lansoprazole (Prevacid)
* Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen (Advil, Motrin, others)
* Omeprazole (Prilosec)
* Ranitidine (Zantac)
* Sertraline (Zoloft)
* Simvastatin (Zocor)
* Ticlopidine (Ticlid)

It's not clear why some people who use these medications develop collagenous colitis or lymphocytic colitis, while others don't.
http://www.mayoclinic.com/health/collag ... sk-factors

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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