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I am beginning this new thread off of what Harma mentioned this morning.
What does the 8 week barrier have to do with Entocort, can someone please explain?
Thanks,
Nancy
Entocort question
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Hi Nancy,
It takes a while for all of the residual budesonide to clear the body, (every chemical has a half-life that relates to their persistence), and after all of it is purged, (or used up), it takes the immune system a while to boost the antibody level back to above the threshold at which a reaction is triggered, (if any food-sensitivities remain in the diet). The accumulated experience of various members here shows that, while it's possible to relapse at any time, especially if they slip up on their diet, anyone who makes it to the 8-week mark, without relapsing, (and without the deterioration of any symptoms), is usually home free.
Tex
It takes a while for all of the residual budesonide to clear the body, (every chemical has a half-life that relates to their persistence), and after all of it is purged, (or used up), it takes the immune system a while to boost the antibody level back to above the threshold at which a reaction is triggered, (if any food-sensitivities remain in the diet). The accumulated experience of various members here shows that, while it's possible to relapse at any time, especially if they slip up on their diet, anyone who makes it to the 8-week mark, without relapsing, (and without the deterioration of any symptoms), is usually home free.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Wooohooo. I am halfway there. My 56th day will be March 13th.
My plan is to get the Enterolab tests ordered this week and have them available. If I flare I'm sending the samples off ASAP. So far, so good.. no new symptoms and I am still rigid on the diet--GF, DF, SF at this time. I am not challenging foods at this time. In fact I think I'll tell my family I'm staying out of all restaurants until the Enterolab results are sent and March 13th gets here.
Oh, and I started vitamin D with no problems. Probably need to look at B12 next. Every week I seem to have (slightly) more energy. What a slow process.
As always, I'm so glad I'm here-- and that you are too.
Carol
My plan is to get the Enterolab tests ordered this week and have them available. If I flare I'm sending the samples off ASAP. So far, so good.. no new symptoms and I am still rigid on the diet--GF, DF, SF at this time. I am not challenging foods at this time. In fact I think I'll tell my family I'm staying out of all restaurants until the Enterolab results are sent and March 13th gets here.
Oh, and I started vitamin D with no problems. Probably need to look at B12 next. Every week I seem to have (slightly) more energy. What a slow process.
As always, I'm so glad I'm here-- and that you are too.
Carol
“.... people will forget what you said, people will forget what you did, but people will never forget how you made them feel.” Maya Angelou
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Carol,
That's great news! Fingers and toes crossed for your recovery plan,
Keep up the good work.
Nancy,
Here's a link to an abstract discussing the Entocort wean off 8 week marker.
Best wishes from Fergus.
Joanna
That's great news! Fingers and toes crossed for your recovery plan,
Keep up the good work.
Nancy,
Here's a link to an abstract discussing the Entocort wean off 8 week marker.
http://www.ncbi.nlm.nih.gov/pubmed/12524408/RESULTS:
Ten patients were randomised to budesonide and 10 to placebo. All 10 patients receiving budesonide had a clinical response compared with two in the placebo group (p<0.001). In the budesonide group, stool weight was reduced from 574 g/day to 200 g/day and stool frequency was reduced from 6.2/day to 1.9/day (p<0.01). The histological inflammation grade in the sigmoid mucosa and the thickness of the collagen layer were significantly reduced. A correlation between the grade of inflammation as well as collagen layer thickness and stool weight was found. No side effects were reported. Eight of 10 patients had relapse of symptoms within eight weeks after stopping treatment.
CONCLUSIONS:
Budesonide is a highly effective and well tolerated treatment of collagenous colitis. There is a high risk of relapse after stopping eight weeks of treatment.
Best wishes from Fergus.
Joanna
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