Mast cells in bowel/intestines

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jmayk8
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Mast cells in bowel/intestines

Post by jmayk8 »

I was reading an article online @
http://thefooddoc.com/mastoctosislinkpage.html
That I thought was interesting... I copied and pasted the below paragraph from it...

WHAT HAPPENS WHEN MAST CELLS ARE TRIGGERED IN THE BOWEL OR ARE INCREASED IN
THE INTESTINES?

When mast cells release histamine and other chemicals in the bowels  this irritates or
inflames the bowel making it more permeable or leaky. In essence it creates a leaky gut
syndrome. This can set up a vicious cycle of pain and further gut injury. In the right setting or genetic predisposition you may develop IBS, colitis, Celiac Sprue, Crohn's disease or a
chronic leaky gut with food intolerance and sensitivity.

I have been on mt mrt diet for a week and I still have gurgles and D. It's def a bit depressing since I had such high hopes. I made an appt with my GI for Wednesday, I want to see what he thinks about prescribing gastrocrom.
Jenny
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tex
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Post by tex »

Jenny,

Are you avoiding foods that are high in histamines, and also foods that trigger mast cell degranulation?

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by jmayk8 »

Yes, trying to but I guess I am still learning about which foods that are mast safe. I just searched on this site and found a good list to follow. I usually always have left overs bc I work a lot and don't have time to cook dinner every night. I am now learning that's a big no-no. Also I guess I am unsure on which foods trigger mast cell degranulation?
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tex
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Post by tex »

Jenny,

Here are some foods that trigger the release of histamine:

Alcohol
Bananas
Chocolate
Eggs
Fish
Milk
Papayas
Pineapple
Shellfish
Strawberries
Tomatoes

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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mbeezie
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Post by mbeezie »

Jenny,

Dr. Scot Lewey who wrote that article is definitley one of our favorites around here. It was the earlier version of that article that got me very interested in mast cells. I wish he could be my gastroenterologist but unfortunately he only sees Colorado residents.

Have you had tests to try to determine if you are having a mast cell problem, such as serum tryptase, urnine n-methylhistamine or an intestinal biopsy. Have you tried antihistamines and gotten some relief? Do you have other symptoms of histamine excess besides D, like itching, headaches, palpitations? Have you tried Histoxym or Histame senzyme supplements? There will need to be some sort of clear indication that you need gastrocrom. BTW, it is sometimes difficult to tolerate and can actually cause D.

What did your dietitian put in your Phase 1 diet? I still had D for a few weeks after starting MRT. After about 6 weeks my D cleared. Sometimes it takes the immune system that long to calm down.

Hang in there.

Mary Beth
"If you believe it will work out, you'll see opportunities. If you believe it won't you will see obstacles." - Dr. Wayne Dyer
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Post by jmayk8 »

I haven't had any tests yet but, I do have the itching and the rash on my chest and thighs after eating and doing anything that makes my blood flow a bit more. I also have a constant runny nose when I eat. I have taken some histamines but have gotten stomach gurgles from them, so maybe I haven't found one I could tolerate. I think it was benedryl that I tried. I just bought histame online but I don't want to try it until I go to my appt tomorrow just invade my dr wants to do any testing. The more research I am doing regarding this I just remembered something when I was younger....I was probably about 20 and was riding in a limo for my grandmothers funeral and someone was wearing this perfume that started to make me have stomach noises. To this day whenever I smell something that I don't like I feel it in my stomach. I know that sounds so over the top but it's true!
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Post by jmayk8 »

Also, I have endometriosis and have read that mast cells have something to do with that as well. I have been trying different meds for my LC but, after a while they just don't work anymore. Making me thing my body has gotten used to them and is now fighting against them. I don't know if this could all be true but, it makes sense to me.
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Post by mbeezie »

Hopefully your doctor will be willing to run some tests. Of course all test could come back normal, which complicates things.

I also get sick from perfume and cologne.

Mary Beth
"If you believe it will work out, you'll see opportunities. If you believe it won't you will see obstacles." - Dr. Wayne Dyer
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